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Topic Name: Obesity Associated With Periodontal Disease
Category: Biomedical
Research persons: M. Jimenez et al.
Location: Harvard, United States
Details
Investigators from the Harvard School of Public Health and the University of
Puerto Rico asked "Is there a prospective association between obesity and
periodontal disease?"
They evaluated the association between different measures of obesity and risk of
periodontal disease. They analyzed data from 36,903 men from the Health
Professionals Follow-Up Study who were free of reported periodontal disease at
the start of follow-up, and we followed them for up to 16 years (1986-2002).
Height was assessed at the start of follow-up, and weight and self-reported
periodontal disease data were collected at baseline and on follow-up
questionnaires mailed every two years. Measures of central obesity were made by
waist and hip circumference through self-assessed measurements and reported in
1987 with the aid of printed instructions and a tape measure. Self-reported
periodontal disease and adiposity measures had been previously validated. They
evaluated the effect of body mass index (BMI kg/m2), waist circumference (WC),
and waist-to-hip ratio (WHR), on first report of periodontal disease diagnosis.
The team observed significant associations between all measures of obesity and
periodontal disease when accounting for age, smoking, race, dental profession,
physical activity, fruit and vegetable intake, and diabetes status at baseline.
Obesity (BMI > 30 kg/m2) at the beginning of follow-up and over follow-up was
significantly associated with a 25% and 29% increased risk compared with normal
weight (BMI 18.5-24.9 kg/m2), respectively. Men with WC > = 40 inches compared
with < 40 inches was significantly associated with a 19% increased risk of
periodontal disease, compared with men with a WC < 40 inches. WHR > = 0.95
compared with < 0.95 exhibited a significant 16% increased risk of periodontal
disease. When BMI was accounted for (i.e., overall obesity), the effects of WC
and WHR (i.e., central obesity) were weakened. The associations of BMI and WC
were significant even among non-diabetics and among those who had never smoked.
These results provide the first evidence following a large group of people over
time with clear evidence of obesity occurring prior to periodontal disease, and
support an association between obesity and risk of periodontal disease. Given
the high prevalence of obesity and periodontal disease, this association may be
of substantial public health importance.
This is a summary of abstract #2913, "Is There a Prospective Association between
Obesity and Periodontal Disease?", by M. Jimenez et al., of the Harvard School
of Public Health and the University of Puerto Rico, presented on April 4, 2009,
at the Miami Beach Convention Center, during the 87th General Session of the
International Association for Dental Research.
| Tags: |
Obesity - Periodontal Disease - Harvard School of Public Health - University of Puerto Rico - obesity and periodontal disease - risk of periodontal disease - waist-to-hip ratio - periodontal disease diagnosis - dental profession - |
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