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Date: 21 November 2009
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Jin Zhang, PhD  

Details of Jin Zhang, PhD

Assistant Professor of Pharmacology

Telephone Number:   (410) 502-0173
Lab: 410-614-2892
Fax Number:   (410) 955-3023
725 North Wolfe St.
Baltimore, MD 21205

Room: 307 Hunterian Building
jzhang32@bs.jhmi.edu

Recent Papers

Zhang J and Allen MD. FRET-based Kinase Biosensors - Illuminating the Kinome. Mol. Biosyst. 2007 In press

Gervasi N, Hepp R, Tricoire L, Zhang J, Lambolez B, Paupardin-Tritsch D and Vincent P. Dynamics of Protein Kinase A Signaling at the Membrane, in the Cytosol, and in the Nucleus of Neurons in Mouse Brain Slices. J. Neurosci. 2007; 27: 2744 - 2750.    [PDF]

Dunn T, Wang C, Colicos MA, Zaccolo M, DiPilato LM, Zhang J, Tsien RY, Feller MB. Imaging of cAMP levels and PKA activity reveals that retinal waves drive oscillations in second messenger cascades. J. Neurosci. 2006; 26:12807-12815.  [PDF]

Qiao Y, Molina H, Pandey A, Zhang J and Cole PA. Chemical Rescue of a Mutant Enzyme in Living Cells. Science 2006; 311:1293-1297. [PDF]

Allen MD, DiPilato LM, Rahdar M, Ren YR, Chong C, Liu JO and Zhang J. Reading Dynamic Kinase Activity in Living Cells for High-throughput Screening. ACS Chem. Biol. 2006; 1:371-376. (Highlighted in Chemical & Engineering News, 84: 48, 2006)  [PDF]

Saucerman JJ, Zhang J, Stenbit AE, Tsien RY and McCulloch AD. Systems Analysis of PKA-mediated Phosphorylation Gradients in Cardiac Myocytes. Proc. Natl. Acad. Sci. USA 2006; 103: 12923-12928[PDF]

Allen MD and Zhang J. Subcellular Dynamics of Protein Kinase A Activity Visualized by FRET-based Reporters. Biochem. Biophys. Res. Commun. 2006; 348: 716-721.  [PDF]


Ni Q, Titov DV and Zhang J. Analyzing Protein Kinase Dynamics in Living Cells with FRET reporters. Methods 2006; 40: 279-286.  [PDF]

Maresh J*, Zhang J* and Lynn DG. The Innate Immunity of Maize and the Dynamic Chemical Strategies Regulating Two-Component Signal Transduction in Agrobacterium tumefaciens ACS Chem. Biol. 2006; 1: 165-175. * Equal contribution.  [PDF]

Ananthanarayanan B, Ni Q, and Zhang J. Signal propagation from membrane messengers to nuclear effectors revealed by reporters of phosphoinositide dynamics and Akt activity Proc. Natl. Acad. Sci. USA 2005; 102: 15081-15086.  [PDF]

Zhang, J.*, Hupfeld, C.J.*, Taylor, S.S., Olefsky, J.M., and Tsien, R.Y. Insulin Disrupts Beta-Adrenergic Receptor Signaling to Protein Kinase A in Adipocytes, Nature 437:569-73, 2005. *Equal contribution. [PDF]

Kunkel, M.T., Ni, Q., Tsien, R.Y., Zhang, J. and Newton, A.C. Spatio-temporal dynamics of protein kinase B/Akt signaling revealed by a genetically-encoded fluorescent reporter, J. Biol. Chem. 280(7):5581-7, 2005. [PDF]

DiPilato, L.M., Cheng, X., and Zhang, J. Fluorescent Indicators of cAMP and Epac Activation Reveal Differential Dynamics of cAMP Signaling within Discrete Subcellular Compartments, Proc. Natl. Acad. Sci. USA 101:16513-16518, 2004. [PDF]

Violin, J.D., Zhang, J., Tsien, R.Y., and Newton, A.C. A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C, J. Cell Biol. 5:899-909, 2003. [PDF]

Zhang, J., Campbell, R.E., Ting, A.Y., and Tsien, R.Y. Creating new fluorescent probes for cell biology, Nature Rev. Mol. Cell Biol. 3: 906-918, 2002. [PDF]

Zhang, J., Ma, Y., Taylor, S.S., and Tsien, R.Y. Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering, Proc. Natl. Acad. Sci. USA 98: 14997-15002, 2001. (Highlighted in Nature Rev. Mol. Cell Biol., 3: 82, 2002.) [PDF]

Zhang, J., Boone, L., Kocz, R., Zhang, C., Binns, A.N., and Lynn, D.G. At the maize/agrobacterium interface: Natural factors limiting host transformation, Chem. Biol., 7: 611-621, 2000. [PDF]

Category: Biological Sciences & Engineering
Type: Scientist & Engineers
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